Dr Stephen O’Keefe talks to ecancer at the Microbiome in Cancer and Beyond 2017 meeting about a recent study that compared and tested the diets of African Americans and native Africans with respect to risk of colorectal cancers.
He found that a Western diet (African Americans) causes an increase in high risk molecules and associated microbiota, the opposite was true for the African diet. A Western diet consists of a higher proportion of fatty and high protein foods, where as the African diet is very high in fibre.
When the diets were switched, a higher risk microbiome was observed in the African sample within two weeks, and the African American group showed suppression. This leads to a suggestion of a high fibre diet of 50g per day as opposed to the USDA 22g (female) and 35g (men) recommendations.
The influence of a Western diet on the Native Alaskan population is also cause for a concern due to their extremely high cancer risk status.